arabidopsisThe Plant Gene Expression Center (PGEC) conducts fundamental research in plant molecular biology. Researchers are elucidating the signal transduction pathways responsible for the perception of environmental and cellular cues. We are exploring disease resistance, light perception, the circadian clock, vegetative growth and the plant-associated microbiome. Essential genes and the networks within which they operate are elucidated using molecular, genetic and biochemical approaches.

The PGEC is a collaboration of the Agricultural Research Service of the U.S. Department of Agriculture and the Plant & Microbial Biology Department of the University of California, Berkeley. The Center's principal investigators are faculty at UC Berkeley, and research opportunities are available in our laboratories for graduate and undergraduate students.

Last? Paper from McCormick Lab

S-Adenosylmethionine, a methyl donor for diverse biological reactions, is synthesized from methionine and ATP. In Arabidopsis, one of the four S-adenosylmethionine synthetase genes, METHIONINE ADENOSYLTRANSFERASE3 (MAT3), is highly expressed in pollen, suggesting that it might play an important role. Indeed, mat3 mutants have impaired pollen tube growth and reduced seed set. Metabolomics analyses confirmed that mat3 pollen and pollen tubes overaccumulate methionine. As a consequence, mat3 pollen has several metabolite profiles different from those of wild type, and disruption of methionine metabolism in mat3 pollen affected transfer RNA and histone methylation levels. Click "Read more" for a link to the publication. Posted 09/12/2016.

More Sequences for Coleman-Derr Lab

A Community Science Project, awarded by the Joint Genome Institute of the Department of Energy, will fund DNA and RNA sequencing, as well as metabolic profiling, of Actinobacteria associated with the roots of sorghum and rice, under both normal and drought conditions. Click "Read more" for details. Posted 09/12/2016.

Harmon Lab News - visiting student and new publication

Cian-Cian Hsieh, a student from National Taiwan University, is visiting the lab this fall. She will be testing whether cold tolerance in maize depends on alternative splicing of key transcripts. To study the relationship between the circadian clock and heterosis, the Harmon lab collaborates with the Z. Jeffrey Chen lab at the University of Texas-Austin. Results from this collaboration were recently published in PL0S Genetics. Ko, D.K., D. Rohozinski, Q. Song, S.H. Taylor, T.E. Juenger, F.G. Harmon, and Z.J. Chen (2016). Temporal shift of circadian-mediated gene expression and carbon fixation contributes to biomass heterosis in maize hybrids. PLoS Genet. 12,e1006197. Click "Read more" for a link to the publication. Posted 08/25/2016.

Welcome to PMB Rotation Students

First year graduate students in the Dept. of Plant and Microbial Biology at UC-Berkeley spend 10 weeks each in 3 different labs, before selecting a home for their thesis project. For the first rotation period, we have 4 students: Michael Busche, who was an undergraduate at Purdue, is rotating in the Fletcher Lab, Lily Gu, who was an undergraduate at Ball State, is rotating in the Lewis Lab; Dhondup Lhama, who was a MCB undergraduate at UC-Berkeley, is rotating in the Hake Lab, and Dhruv Patel, who was an undergraduate at Cornell, is rotating in the Harmon Lab. Posted 08/23/2016.

Fellowship Award

Dat Dao, a graduate student in the Fletcher lab, was recently awarded the 2016-2017 Grace Kase Graduate Fellowship. This fellowship was established to support UC Berkeley graduate students pursuing research in plant biology or microbiology. It was awarded to Dat for his “excellent academic and rotation performance” during his first year as a PMB graduate student. Posted 06/16/2016.

Two New Papers Published from Quail Lab

A collaboration with Elena Monte, a former postdoc in the Quail Lab and now a professor in Barcelona, has yielded two new manuscripts, one in the Proceedings of the National Academy of Sciences USA, and one in Nature Communications. The manuscripts address how the circadian clock and light signaling pathways converge, and how signaling between the chloroplast and nucleus affect a key regulator of a light-induced transcriptional network. The PNAS paper was highlighted in Faculty1000, a website ( that features notable papers. Click "Read more" for details. Posted 05/08/2016.

Kudos to Baker Lab Undergraduates

Noah Gardner is the Plant and Microbial Biology Citation Recipient for 2015-2016, for distinguished undergraduate work. Noah did his Honors Thesis Project, "Modulation of Plant Innate Immunity through DCL4-dependent miRNAs", in the Baker lab. In May 2015, Jackie Wright received the Melis Medal for her Outstanding Research Presentation of her Honors Thesis Project, "Novel miRNAs in the Regulation of Plant Innate Immunity", at the CNR Honors Symposium. Jackie was also awarded a Sponsored Projects for Undergraduate Research (SPUR) student-initiated project ($2000) for research in the Baker lab, which included a travel award to attend the 2014 Cell Symposium: Regulatory RNAs, organized by Jennifer Doudna and Richard Gregory. Click "Read more" to find out what Noah and Jackie are doing now. Posted 04/30/2016.

Arrivals and Departures

Annis Richardson has joined the Hake lab as a postdoctoral fellow. She did her Ph.D. with Enrico Coen at the John Innes Centre in Norwich, England. She will apply her expertise in modeling to the maize leaf projects in the Hake lab. Peter DiGennaro, currently a postdoc in the Fletcher Lab, will be leaving at the end of May. He obtained a tenure track faculty position in Molecular Nematology at the University of Florida, in the Department of Entomology and Nematology. His last day in the lab will be May 31, and he and his family will be moving to Gainesville in June. Posted 05/05/2016.


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